Palmitoyl Tripeptide-1
Matrixyl 3000 (Pal-GHK)
What It Does
A signal peptide that mimics a collagen breakdown fragment, triggering collagen synthesis. One half of the Matrixyl 3000 pair, clinically shown to reduce wrinkle depth and improve firmness.
How to Use It
Apply in serum or moisturiser form, morning or evening. Works best in combination with palmitoyl tetrapeptide-7.
Comedogenic Rating
Non-comedogenic. This ingredient is considered non-comedogenic and is unlikely to clog pores or contribute to acne breakouts.
Pregnancy Safety
Palmitoyl Tripeptide-1 is considered safe for use during pregnancy. Always consult your OB or midwife before making significant changes to your skincare routine during pregnancy.
This information reflects general dermatological consensus and is not a substitute for personalised medical advice.
Sensitivity Risk
Sensitivity risk rated Low. This ingredient is generally well-tolerated. Patch testing is recommended if you have reactive skin.
Pairs Well With
Avoid Mixing With
Frequently Asked Questions
Does palmitoyl tripeptide-1 really work?
Yes. A double-blind clinical study published in the International Journal of Cosmetic Science found Matrixyl 3000 (this peptide + palmitoyl tetrapeptide-7) significantly reduced wrinkle volume and improved skin tone.